Ausgabe 2/2023
Inhalt (11 Artikel)
A T-cell antigen atlas for meningioma: novel options for immunotherapy
Gioele Medici, Lena K. Freudenmann, Julia Velz, Sophie Shih-Yüng Wang, Konstantina Kapolou, Nagarajan Paramasivam, Lena Mühlenbruch, Daniel J. Kowalewski, Flavio Vasella, Tatjana Bilich, Beat M. Frey, Marissa L. Dubbelaar, Angelica Brooke Patterson, Anna Maria Zeitlberger, Manuela Silginer, Patrick Roth, Tobias Weiss, Hans-Georg Wirsching, Niklaus Krayenbühl, Oliver Bozinov, Luca Regli, Hans-Georg Rammensee, Elisabeth Jane Rushing, Felix Sahm, Juliane S. Walz, Michael Weller, Marian C. Neidert
Tau seeding and spreading in vivo is supported by both AD-derived fibrillar and oligomeric tau
Anastasie Mate De Gerando, Lindsay A. Welikovitch, Anita Khasnavis, Caitlin Commins, Calina Glynn, Joshua E. Chun, Romain Perbet, Bradley T. Hyman
Mutation ∆K281 in MAPT causes Pick’s disease
Manuel Schweighauser, Holly J. Garringer, Therése Klingstedt, K. Peter R. Nilsson, Masami Masuda-Suzukake, Jill R. Murrell, Shannon L. Risacher, Ruben Vidal, Sjors H. W. Scheres, Michel Goedert, Bernardino Ghetti, Kathy L. Newell
Transcriptomic profiling of Parkinson's disease brains reveals disease stage specific gene expression changes
Chiara Cappelletti, Sandra Pilar Henriksen, Hanneke Geut, Annemieke J. M. Rozemuller, Wilma D. J. van de Berg, Lasse Pihlstrøm, Mathias Toft
Mutant LRRK2 exacerbates immune response and neurodegeneration in a chronic model of experimental colitis
Diego Cabezudo, George Tsafaras, Eva Van Acker, Chris Van den Haute, Veerle Baekelandt
Central and peripheral myeloid-derived suppressor cell-like cells are closely related to the clinical severity of multiple sclerosis
María Cristina Ortega, Rafael Lebrón-Galán, Isabel Machín-Díaz, Michelle Naughton, Inmaculada Pérez-Molina, Jennifer García-Arocha, Jose Manuel Garcia-Dominguez, Haydee Goicoechea-Briceño, Virginia Vila-del Sol, Víctor Quintanero-Casero, Rosa García-Montero, Victoria Galán, Leticia Calahorra, Celia Camacho-Toledano, María Luisa Martínez-Ginés, Denise C. Fitzgerald, Diego Clemente
From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions
Assia Tiane, Melissa Schepers, Rick A. Reijnders, Lieve van Veggel, Sarah Chenine, Ben Rombaut, Emma Dempster, Catherine Verfaillie, Kobi Wasner, Anne Grünewald, Jos Prickaerts, Ehsan Pishva, Niels Hellings, Daniel van den Hove, Tim Vanmierlo
Defective cerebellar ryanodine receptor type 1 and endoplasmic reticulum calcium ‘leak’ in tremor pathophysiology
Regina T. Martuscello, Meng-Ling Chen, Steven Reiken, Leah R. Sittenfeld, David S. Ruff, Chun-Lun Ni, Chih-Chun Lin, Ming-Kai Pan, Elan D. Louis, Andrew R. Marks, Sheng-Han Kuo, Phyllis L. Faust
Individual myasthenia gravis autoantibody clones can efficiently mediate multiple mechanisms of pathology
Minh C. Pham, Gianvito Masi, Rosa Patzina, Abeer H. Obaid, Seneca R. Oxendine, Sangwook Oh, Aimee S. Payne, Richard J. Nowak, Kevin C. O’Connor
SCA34 caused by ELOVL4 L168F mutation is a lysosomal lipid storage disease sharing pathology features with neuronal ceroid lipofuscinosis and peroxisomal disorders
Benjamin Ellezam, Matsanga L. Kaseka, Dang Khoa Nguyen, Jean Michaud
AMFR dysfunction causes autosomal recessive spastic paraplegia in human that is amenable to statin treatment in a preclinical model
Ruizhi Deng, Eva Medico-Salsench, Anita Nikoncuk, Reshmi Ramakrishnan, Kristina Lanko, Nikolas A. Kühn, Herma C. van der Linde, Sarah Lor-Zade, Fatimah Albuainain, Yuwei Shi, Soheil Yousefi, Ivan Capo, Evita Medici van den Herik, Marjon van Slegtenhorst, Rick van Minkelen, Geert Geeven, Monique T. Mulder, George J. G. Ruijter, Dieter Lütjohann, Edwin H. Jacobs, Henry Houlden, Alistair T. Pagnamenta, Kay Metcalfe, Adam Jackson, Siddharth Banka, Lenika De Simone, Abigail Schwaede, Nancy Kuntz, Timothy Blake Palculict, Safdar Abbas, Muhammad Umair, Mohammed AlMuhaizea, Dilek Colak, Hanan AlQudairy, Maysoon Alsagob, Catarina Pereira, Roberta Trunzo, Vasiliki Karageorgou, Aida M. Bertoli-Avella, Peter Bauer, Arjan Bouman, Lies H. Hoefsloot, Tjakko J. van Ham, Mahmoud Issa, Maha S. Zaki, Joseph G. Gleeson, Rob Willemsen, Namik Kaya, Stefan T. Arold, Reza Maroofian, Leslie E. Sanderson, Tahsin Stefan Barakat