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Erschienen in: Aesthetic Plastic Surgery 2/2024

Open Access 11.10.2023 | Original Articles

Subclinical Upper Eyelid Ptosis in Asian Patients: The Role of Levator Advancement in Optimizing Outcomes in “Cosmetic” Upper Blepharoplasty

verfasst von: Chin-Ho Wong, Michael Ku Hung Hsieh, Bryan Mendelson

Erschienen in: Aesthetic Plastic Surgery | Ausgabe 2/2024

Abstract

Background

Subclinical ptosis is prevalent in Asian patients presenting for aesthetic upper blepharoplasty. To achieve predictable and satisfactory results in these patients, addressing the ptosis component is critical. In this paper, we present a precision levator advancement technique that enabled us to predictably incorporate the levator advancement into our upper blepharoplasty to deliver more predictable results in these patients.

Materials and Methods

Asian patients with normal or near normal margin to reflex distance 1 (MRD 1 of ≥ 3.5 mm) and symptoms and signs of straining of the frontalis with eyelid opening were diagnosed with subclinical upper eyelid ptosis and included in this prospective study. The advancement required was estimated pre-operatively using a formula that we developed. Our surgical technique is presented in detail here, and our long-term results were analysed.

Results

From December 2019 to August 2022, 97 patients were included in this study. Sixty-five patients were primary cases and 32 were revision cases. The mean follow-up was 15 months. Of the 192 eyelids analysed, our formula was able to correctly identify the required fixation location in 69% of eyelids. In majority of the eyelids (94%), the correct location of fixation location within +/− 1 mm of the estimated location. All patients (100%) were satisfied with their long-term results. Our revision rate was 3%.

Conclusions

Incorporating a precisely done levator advancement into the upper blepharoplasty in patients with subclinical ptosis is critical for optimizing the aesthetic and functional outcomes. This approach has enabled us to perform this procedure greater predictably in this group of patients.

Level of Evidence III

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.​springer.​com/​00266.
Begleitmaterial
Video #1: This video explains our system of assessment of brow elevation with eye opening (MP4 57170 kb)
Video #2: This video shows our pre-operative determination of levator advancement fixation locations relative to the musculoaponeurotic junction (MAJ) based on our system of assessment (Table 1) for our surgical demonstration patient (MP4 41275 kb)
Video #3: This video shows our surgical technique (MP4 124762 kb)
Video #4: This video shows the recovery process and long-term cosmetic and functional results of our surgical demonstration patient (MP4 31351 kb)
Video #5: This video shows the functional outcomes of our patients presented in Figs. 4, 6, 7 and 8 (MP4 39006 kb)
Hinweise

Supplementary Information

The online version contains supplementary material available at https://​doi.​org/​10.​1007/​s00266-023-03697-1.
‘The aim of argument, or of discussion, should not be victory, but progress’ – Joseph Joubert.

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Introduction

“Asian upper blepharoplasty” is one of the most common cosmetic procedures done in Asia [1, 2]. The aim of the surgery is to create attractive and brighter eyes. Much of the emphasis in the literature on Asian upper blepharoplasty focuses on fold creation techniques, to achieve the desired height, symmetry and shape of the upper eyelid crease [14]. Many papers noted that creating the double eyelid crease in patients without one gives the visual illusion of widening of the palpebral aperture [57]. However, the actual widening or optimization of the palpebral apertures to deliver better aesthetic and functional results are rarely discussed in cosmetic Asian upper blepharoplasty. In Caucasian patients, blepharoplasty with concurrent levator palpebrae superioris (LPS)/Muller muscle surgery to widen the palpebral aperture to deliver better aesthetic and functional results is an accepted concept. Carraway was a proponent for blepharoplasty with concurrent upper eyelid ptosis correction as early as the late 1980s [8, 9]. This concept was also advocated by many other surgeons [1012]. Massry refers to a “cosmetic ptosis repair” and Martin similarly discussed the foundation of good upper lid surgical results as the requirement for “ptosis repair in aesthetic blepharoplasty” [11, 13].
Because Asian upper blepharoplasty is quite different from Caucasian upper blepharoplasty, this concept of optimizing function with upper blepharoplasty has not been widely emphasized or practised in the former [14]. However, leading thinkers in Asian upper blepharoplasty have increasingly stressed the need to optimize function as a prerequisite for satisfactory results. Chen noted that in Asian upper blepharoplasty, “decreased levator function and latent ptosis are commonly missed”, with the recommendation that “even mild 1–2 mm ptosis should be separately corrected before any attempt to create a double eyelid crease” for ideal results [15]. This is necessary because having the qualities of attractive or beautiful eyes are all built upon optimally functioning levator mechanisms of the upper eyelids [1, 4, 6, 16]. With this critical prerequisite of the attractive upper eyelid fulfilled, other cosmetic aspect of the upper eyelid such as the height, crispness and symmetry of the eyelid crease may be more reliably and predictably achieved.
While the benefits of incorporating the levator advancement into the upper blepharoplasty of Asian patients with subclinical ptosis is increasingly accepted, to achieve the desired results, the surgeon would have to upgrade their procedure from a “simple” cosmetic upper blepharoplasty to a cosmetic and functional upper blepharoplasty. There are risks inherent to this procedure, specifically causing asymmetry to the palpebral aperture from over- or under-correction. The clinical threshold for more widespread adoption of this approach would be the development of technical advancements that deliver greater precision while minimizing complications. We have previously published our approach to the levator advancement procedure which allows us to perform this procedure with greater predictability and low revision rates [1720]. This approach may be applied to patients with subclinical ptosis, both in primary or revisional cases. This paper details our experience and outcomes with this approach in this cohort of patients.

Patient Selection

Patients who presented for upper blepharoplasty and met the following inclusion criteria were diagnosed with subclinical ptosis and included in this study:
(1)
Asian ethnicity
 
(2)
Normal or near normal palpebral aperture: Margin to reflex distance 1 (MRD 1) of + 4.5 mm (normal aperture) to + 3.0 mm (mild ptosis of < 1.0 mm) [21, 22].
 
(3)
Excellent or good levator function (≥ 10 mm).
 
(4)
Symptoms of heaviness, straining or difficulty with opening their upper eyelids
 
(5)
Signs of unilateral or bilateral frontalis activation with eye opening: Frontalis straining was quantitated by brow elevation with eyelid opening [17].
 
Patient with more significant degree of ptosis (MRD 1 < 3 mm) were excluded. Patients with pre-existing lid retraction were also excluded from this study. The cohort of patients included in this study would be one that would conventionally be offered cosmetic upper blepharoplasty only without any levator manipulation. Only patients with at least 1-year follow-up were included in this study.

Material and Methods

From December 2019 to August 2022, 97 patients were prospectively included in this study. In total, 192 upper eyelids (2 patients had unilateral procedure) were analysed in this study. Sixty-five patients were primary cases and 32 were revision cases. There were 79 female patients and 18 male patients. The mean age of the patients were 41 years of age (range 16–68). The mean follow-up time was 15 months (range 12–35). Standard pre- and post-operative photographs were used for comparison. Patients subjectively rated the outcomes of their surgery with a Likert-type scale of eyelid appearance: 0—worse; 1—unchanged; 2—improved; and 3—markedly improved.

Pre-Operative Determination of Levator Advancement Fixation Location

We have previous published our method of pre-operatively estimating the location of suture placement relative to the musculoaponeurotic junction (MAJ) of the levator of the upper eyelid [17, 18]. Table 1 shows our updated formula. To increase the precision of our estimation, we have refined our elevation of the upper eyelid required (A) into incremental categories of + 0.5 mm. Brow elevation (B) has been refined into finer subcategories to reflect a greater range of clinical manifestations of the degree of frontalis strain (please see Video #1 that explains our assessment of brow elevation) [23]. This system of assessment was used to evaluate out patients pre-operatively and the estimated locations of suture placement determined. Please see Video #2 that illustrates the pre-operative planning for our surgical demonstration patient.
Table 1
Our formula for determining the levator advancement needed for Asian patients
Ptosis correction needed (A)
Brow elevation with eye opening (B)
Eye dominance (C)
0 mm: − 5.0
Absent: + 0
Dominant eye: + 0
0.5 mm: − 4.5
Mild minus: + 0.5
Co-dominant eye: + 0
1 mm: − 4.0
Mild: + 1
Non-dominant EYE: + 1
1.5 mm: − 3.5
Moderate minus: + 1.5
 
2 mm: − 3.0
Moderate: + 2
 
2.5 mm: − 2.5
Severe minus: + 2.5
 
3 mm: − 2.0
Severe: + 3
 
3.5 mm: − 1.5
  
4 mm: − 1.0
  
4.5 mm: − 0.5
  
5 mm: 0
  
These values are referred from the musculoaponeurotic junction (MAJ) of the levator of the upper eyelid, with a value of 0 mm denoting the location of the MAJ and negative and positive values denoting distance below and above this landmark, respectively. Parameter A is the amount of upper eyelid elevation needed, B is the degree of brow elevation present with eye opening and C is for eye dominance. Summation of these 3 parameters gives a value that is the expected levator advancement needed for that eyelid
Estimated distance (in mm) from the musculoaponeurotic junction to anterior tarsus for the levator advancement = A + B + C

Surgical Technique

Markings: The lower incision is marked at 8.0–9.5 mm from the ciliary margins with the skin under slight tension. Skin excision is done very conservatively and kept within the zone of thin skin in the upper eyelids and ranges from 2 to 8 mm. The locations of the mid-pupil line, medial and lateral corneal–scleral limbus are marked. These are the horizontal fixation locations for our levator advancement sutures. The procedure may be done under local anaesthesia or light intravenous sedation. Local anaesthetic consisted of a mixture of 10 cc 1% lignocaine, 10 cc 1% Ropivacaine and 0.1 cc of 1:1000 adrenaline (giving a dilution of 1:200,000 of the concentration of the adrenaline in the anaesthetic mixture). Approximately 1.0 cc of the local anaesthesia is administered per upper eyelid.
Video #3 demonstrates our surgical technique [17]. After skin excision, the pre-tarsal orbicularis oculi is lifted off the levator mechanism. A strip of pre-tarsal orbicularis is excised (Fig. 1a). The orbital septum is then carefully opened. The landmark to identify here is the discrete fat pad that is the lateral extension of the central upper eyelid fat pad. Below this, the lower edges of the levator aponeurosis will be visible as a distinctive “white line” [24]. Once identified, the assistant then picks up and retracts the lower edge of the levator aponeurosis caudally. With the surgeon picking up the orbital septum to provide the countertraction to keep the orbital septum under slight tension, the orbital septum may then be safely and completely open across the upper eyelid to expose the levator aponeurosis and the musculoaponeurotic junction (Fig. 1b). The fibrous tissue that is the fusion of the orbital septum and the levator aponeurosis may be conservatively excised over the expected fixation points for the levator advancement to enable clear visualization of the upper edge of the tarsus (Fig. 1c).
According to the pre-operatively determined advancement location, the advancement point is precisely marked on the levator relative to the musculoaponeurotic junction (Fig. 1d and e). A 6/0 double arm non-cutting suture was used for this purpose (Ethicon Inc. reference 8610H). The suture is placed from this point through the levator aponeurosis or muscle (staying above the Muller muscle). A firm bite is then taken of the tarsus 2 mm below the upper edge directly below the entry point on the levator and then passed back to the same location on the levator approximately 2 mm medial to the entry point (Fig. 1f). The suture is then firmly tied. The procedure is then repeated on the contralateral eyelid and a levator advancement fixation suture placed in a similar manner. The patient is then sat up and asked the open the eyelids. The adequacy of the palpebral aperture and symmetry is checked. The palpebral aperture should be exactly the intended correction without over- or under-correction. If the aperture is suboptimal, the levator advancement location may be adjusted as needed. If the palpebral aperture is satisfactory, the levator advancement may then be reinforced at the level of the medial and lateral corneal–scleral limbus at the same distance from the musculoaponeurotic junction (MAJ) with 2 more fixation sutures. In total, three levator advancement fixation sutures are placed per upper eyelid. After placement of all three sutures, the patient is then sat up for a final check for adequacy and symmetry of the palpebral aperture before final closure. The dermis is then sutured to the lower edge of the levator aponeurosis with a 7/0 Vicryl suture to create a crisp upper eyelid crease. This was reinforced with the skin closure with 6/0 Ethilon suture in a skin–levator–skin manner.

Results

Majority of the patients were satisfied with the results with all patients reporting that their appearance has either improved or markedly improved at 1-year follow-up. The formula was able to predict the correct fixation location is 132 of the 192 eyelids analysed (69%). It was able to correctly predict the correct placement location to within +/− 1 mm in 180 of the 192 eyelids analysed (94% of patients). In 98 % of patients, the fixation location was within +/− 2 mm of the estimated location. Figures 2, 3, 4, 5, 6, 7, 8 and 9 demonstrate our results in a range of patients. Figures 2, 3, 4, 5 and 6 demonstrate outcomes in younger patients with subclinical eyelid ptosis. The levator advancement delivered superior aesthetic as well as functional outcomes for these patients. Figures 7 and 8 show older patients with subclinical ptosis. The need for the levator advancement is easier to understand in these patients. While their pre-operative MRD 1 is normal or “near normal”, usually more severe degree of frontalis strain is evident and it would be quite obvious that their aperture is held in its pre-operative level by the activation of the frontalis muscle. In these patients, the aim of the levator advancement is to adequately restore the intrinsic eye opening, negating the need for the frontalis compensation while precisely controlling the desired palpebral aperture. Post-surgery, the aperture is effectively maintained or only slightly enhanced while the frontalis strain would be significantly eliminated. The final category would be patients that present with subclinical ptosis after previous blepharoplasty (Fig. 9). Cosmetic upper blepharoplasty has the effect of exacerbating the mild ptosis patients may have pre-operatively. This would manifest post-surgery with worsening of the upper eyelid asymmetry and frontalis straining. This is also known as post-upper blepharoplasty syndrome (PUBS) [25]. These patients may be treated effectively with precision levator advancement as presented here. Video #4 shows the recovery and long-term cosmetic and functional results of our surgical demonstration patient. Video #5 demonstrates the long-term cosmetic and functional results of some of our patients (presented in Figs. 4, 6, 7 and 8). Our revision rate was 3% (3 of the 97 patients). All 3 patients required minor revisions of removal of residual skin excesses only. None of our patients required revision of the palpebral aperture.

Discussion

We have previously published and validated our approach to upper eyelid ptosis correction in Asian patients using the musculoaponeurotic junction formula [17, 18]. The advantage of this approach is that it enables the surgeon to quite accurately determined the location for the levator advancement suture placement pre-operatively from a constant anatomical landmark. Having this information is invaluable as the surgeon would know exactly where to start and exactly how to proceed to adjust the fixation (if needed) to achieve the desired correction. We have refined our formula to smaller increments of +0.5 mm in the elevation of the eyelid required (Parameter A) and the degree of brow elevation observed with eye opening (Parameter B) [17, 18, 23]. In our experience reported here, this refined formula has greater accuracy in estimating the fixation locations and hence less need for intraoperative adjustments. Increased accuracy is needed to perform the levator advancement in patients with subclinical ptosis. In these patients, the margin for error is narrower, and therefore, greater precision in the pre-operative planning is important for successful outcomes.
Subclinical ptosis is a compensated state of eyelid opening in which the upper eyelid is maintained at normal or near normal position by activation of the frontalis muscle [26, 27]. In the literature, “subclinical” or “latent” blepharoptosis is not a clearly defined entity with varied descriptions [2, 15, 2832]. Choi et al. described subclinical ptosis as when the “upper lid level is more than 1 millimetre below the proper level of the cornea” as suggestive of its presence [29]. Kim et al. stated that objective blockage of the superior cornea of > 2 millimetre by the upper lid as diagnostic of subclinical ptosis. They also alluded that a pre-operative frontalis strain as identifiers of subclinical ptosis [28]. Li et al. suggested that the clinical findings of slightly asymmetrically high skin crease, eyebrow position or eyelid margin were diagnostic of “latent aponeurotic ptosis” [30]. These descriptions would be consistent with the definition of subclinical upper eyelid ptosis as used in this paper.
Subclinical ptosis is much more common is Asian patients [2]. The reason for this is anatomical as most Asian patients have a less robust eyelid opening mechanism compared with Caucasian patients. The levator aponeurosis inserts into the antero-superior surface of the tarsus. In patients with crisp, naturally occurring upper eyelid creases, fibres originating from the lower edges of the levator aponeurosis inserts into the dermis at the location of the eyelid crease to invaginate the skin and form the eyelid crease with eyelid opening [14, 33, 34]. Both these anatomical attachments, the anterior tarsus and dermis, contribute to the ability of the levator palpebrae superioris to elevate the upper eyelid. Patients with absent or poorly formed eyelid crease have suboptimal eye opening for the following reasons: (1) The absent or poorly developed dermal attachment weaken the ability of the levator palpebrae superioris to open the eyelids and (2) The poorly formed dermal attachments to the upper eyelid skin are surrogate indicators that the quality of levator aponeurosis to the anterior tarsus attachments are less robust. Therefore, these patients may inherently have a weaker eye-opening ability from young. Commonly, these are also patients that present for Asian upper blepharoplasty. Therefore, the need for subclinical ptosis correction among young Asian patients may be quite high [28, 30, 32]. Kim et al. reported that 30% of young Korean patients presenting for cosmetic blepharoplasty would require their subclinical ptosis treated [28]. In older patients, a higher percentage would require the levator advancement due to involution weakening from a baseline that was already less than optimal [16]. Therefore, for older Asian patients presenting for either primary or revision upper blepharoplasty who fulfil the diagnostic criteria for subclinical ptosis will require the levator advancement to achieve good aesthetic and functional results.
Clinically, most younger patients are asymptomatic. Older patients and patients for revision blepharoplasty may complain of heaviness, straining to keep their eyes open and even headache towards the end of the day [28, 35, 36]. A key diagnostic feature is the frontalis strain with elevation of the brow with eyelid opening [35]. Incorporating the levator advancement into their upper eyelid surgery is beneficial for two reasons. First, patients with suboptimal eyelid opening at the lower range of normal will benefit aesthetically and functionally with slight tightening of the levator mechanism. This creates wider apertures which are more attractive/brighter with more effective eyelid opening. Secondly, cosmetic upper blepharoplasty, with the associated dissection and post-operative swelling, done in this group of patients quite often will result in attenuation or further weakening of the eyelid opening mechanism. This is manifested by various degrees of asymmetry in the palpebral aperture, worsening of the compensatory elevation of the brow with eye opening resulting in exacerbation of brow asymmetry and poorly formed or uneven upper eyelid creases. This has been called post-blepharoplasty syndrome (PUBS) by Steinsapir and Kim [25]. They noted the cause of PUBS to be due to detachment of the levator insertion onto the tarsus from scarring and contracture of the orbital septum post-surgery. Therefore, addressing the subclinical ptosis at the primary surgery is needed to prevent the development of PUBS. The revision rates for cosmetic blepharoplasty are reported to be as high as 12–52% [25, 37, 38]. Commonly, the reasons for these revisions include asymmetry of the upper eyelid creases, poorly formed creases or asymmetric apertures. A great majority of these cases may have post-upper blepharoplasty syndrome (PUBS) as an identifiable cause [25]. The treatment for this is to incorporate levator advancement into the revision upper blepharoplasty to optimize both the aesthetic and function aspects of the upper eyelids (Fig. 10).
The advantages of this approach over conventional upper blepharoplasty approaches (that focuses on crease creation only in this group of patients) are that the aesthetic results attainable are superior and more predictable. In addition to asymmetries in the upper eyelid creases, minor pre-operative asymmetries in the aperture width, which are quite commonly seen, may be addressed at the same time as well with the levator advancement. As importantly, functionally, patients will notice that their upper eyelid opening is more effective and easier after the surgery. Most patients are very appreciative of this functional improvement. The disadvantages are that the surgery is slightly more complicated and the dissection slightly more extensive. Swelling and bruising are slightly more, but with meticulous technique and post-surgical care, this may be minimized. The precision levator advancement required for this technique also has a steeper learning curve than conventional approaches.

Conclusions

The advantages of our approach described in this paper in Asian patients with subclinical ptosis are as follows: (1) The aesthetic results attainable is superior to techniques that focus on crease formation only, without direct manipulation of the levator mechanism. This technique widens and equalizes the palpebral apertures. It can deliver a more symmetrical and crisp upper eyelid creases, and eliminate frontalis strain while relaxing the brows to a more aesthetic and symmetrical positions. (2) Functionally, the intrinsic eye-opening mechanism is also optimized. Patients feel less peri-ocular strain and are able to open their eyelids more effectively, eliminating the sensation of straining needed to keep the eyelids open. Patients are profoundly appreciative of these functional benefits. It is important to realize that in the upper eyelid, function and aesthetics are intricately related [39]. Thus, it is necessary to optimize function to be able to achieve the desired cosmetic results predictably. This understanding represents a paradigm shift in Asian upper blepharoplasty.

Declarations

Conflict of interest

The authors declare no conflict of interest in this present work. None of the authors has a financial interest in any of the products, devices or drugs mentioned in this manuscript.

Ethical Approval

This study was performed in accordance with the ethical standards of our institution and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
Patients provided their written informed consent for their participation in this study.
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://​creativecommons.​org/​licenses/​by/​4.​0/​.

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Supplementary Information

Below is the link to the electronic supplementary material.
Video #1: This video explains our system of assessment of brow elevation with eye opening (MP4 57170 kb)
Video #2: This video shows our pre-operative determination of levator advancement fixation locations relative to the musculoaponeurotic junction (MAJ) based on our system of assessment (Table 1) for our surgical demonstration patient (MP4 41275 kb)
Video #3: This video shows our surgical technique (MP4 124762 kb)
Video #4: This video shows the recovery process and long-term cosmetic and functional results of our surgical demonstration patient (MP4 31351 kb)
Video #5: This video shows the functional outcomes of our patients presented in Figs. 4, 6, 7 and 8 (MP4 39006 kb)
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Metadaten
Titel
Subclinical Upper Eyelid Ptosis in Asian Patients: The Role of Levator Advancement in Optimizing Outcomes in “Cosmetic” Upper Blepharoplasty
verfasst von
Chin-Ho Wong
Michael Ku Hung Hsieh
Bryan Mendelson
Publikationsdatum
11.10.2023
Verlag
Springer US
Erschienen in
Aesthetic Plastic Surgery / Ausgabe 2/2024
Print ISSN: 0364-216X
Elektronische ISSN: 1432-5241
DOI
https://doi.org/10.1007/s00266-023-03697-1

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