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Archives of Orthopaedic and Trauma Surgery

Erschienen in:

26.10.2021 | Arthroscopy and Sports Medicine

Use of tranexamic acid in medial open wedge high tibial osteotomy

verfasst von: Wolf Petersen, Mats Bentzin, Sebastian Bierke, Hi Un Park, Martin Häner

Erschienen in: Archives of Orthopaedic and Trauma Surgery | Ausgabe 9/2022

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Abstract

Purpose

Aim of this study was to evaluate the effect of tranexamic acid (TXA) on the outcome after medial open wedge osteotomy.

Material and methods

A prospective non-randomized comparative study with 52 patients has been performed. In both treatment groups, the same surgical technique for the medial open wedge HTO was used. In group 1 (N: 26) the patients received 1 g TXA i.v. preoperatively, in group 2 (N: 26) no TXA was given. Primary outcome measure was the decrease in hemoglobin concentration. Secondary outcome criteria were postoperative pain, intraarticular effusion (measured by ultrasound), range of motion (ROM) at discharge, peri- and postoperative complications and the KOOS PS (pre- and postoperatively at 1 year follow up).

Results

Hemoglobin decrease was significantly less in the TXA group compared to the non TXA group. Postoperative pain and intraarticular effusion was also significantly lower and ROM at discharge was higher in the TXA group. There was no group difference in peri- and postoperative complications and the pre- and postoperatively KOOS PS.

Conclusions

The results of the present study show the systemic application of 1 g TXA reduces hemoglobin drop and postoperative morbidity (pain, intraarticular effusion, and ROM) after tibial open wedge HTO.

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Titel: Use of tranexamic acid in medial open wedge high tibial osteotomy
verfasst von: Wolf Petersen
Mats Bentzin
Sebastian Bierke
Hi Un Park
Martin Häner
Publikationsdatum: 26.10.2021
Verlag: Springer Berlin Heidelberg
Erschienen in: Archives of Orthopaedic and Trauma Surgery / Ausgabe 9/2022
Print ISSN: 0936-8051
Elektronische ISSN: 1434-3916
DOI: https://doi.org/10.1007/s00402-021-04219-x

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